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Sensor to Monitor Battery Condition, Prolong Battery Life, and Prevent Ignition
Tomáš Syrový, a scientist at the University of Pardubice, is working on a new generation of smart batteries that could monitor their capacity and restore it if necessary. They could be used, for example, in electric cars or stationary battery storage systems. "Sensors surround us today in all our ac…
Three New Professors at the University of Pardubice
The University of Pardubice has three new professors as of today. Scientifically and pedagogically, all three women work at the Faculty of Chemical Technology, each in a different field. Their appointment decree was personally handed over to them today at Prague Castle by the President of the Czech …
Scientist from the University of Pardubice receives prestigious European grant for research on lipids
Michal Holčapek, a chemist from the University of Pardubice, and three other scientists from the Czech Republic received a highly prestigious grant from the European Research Council (ERC). The scientist, who works for the Faculty of Chemical Technology, has long been involved in analysing lipids an…
Covid Filter for Developing Countries
Scientists at the Centre for Materials and Nanotechnologies, Faculty of Chemical Technology, University of Pardubice, have developed a personal filter against SARS-CoV-19 that could find its application in developing countries. Fitting into a backpack, the entire assembly does not use nanomateria…
Prof. Holčapek receives prestigious USA award
Analytical chemist Michal Holčapek from the University of Pardubice received the Herbert J. Dutton Award in the USA as the first Czech ever. The credit for this goes to his many years of research on lipids at the Faculty of Chemical Technology. Among other results, this has led to a method that a…
UPCE smart sensors to save water usage
A smart environmental sensor to help farmers manage irrigation efficiently is a discovery by the researchers from the Faculty of Chemical Technology at the University of Pardubice and their partners. The novelty in the field of material printing can measure both soil moisture and temperature, thu…
The university receives a patent for pancreatic cancer diagnosis
The method for diagnosing pancreatic cancer developed by the analytical chemist Michal Holčapek from the Faculty of Chemical Technology, University of Pardubice has received a European patent. Holčapek’s scientific group has described a procedure for early cancer detection based on blood analysis…
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- Introduction
New analysis to find biomarkers of tumors in tissue with laser desroption/ionization mass spectrometry of small molecules in hope of future early diagnoses of cancer.
The project deals with the development of matrix-assisted and matrix-free laser desorption/ionization mass spectrometry (MA)LDI-MS for the analysis of small molecules in biological samples. Samples of rat urine, plasma and tissues will be obtained after selected drug administration together with placebo samples with subsequent drug metabolite analysis. Further, samples of human tissues (health x tumor) will be analyzed with the aim to obtain information about present biomarkers of tumor disease and possible future application
in the early clinical diagnostics. Particular samples will be characterized using MALDI imaging to obtain 2D images with the information about present small molecules, their amount and distribution in studied tissues.
Parallel measurements using ultra high performance liquid chromatography/atmospheric pressure ionization tandem mass spectrometry (UHPLC/API-MS/MS) will be performed for the proling of individual group of compounds with the emphasis on the elemental composition determination based on the high mass accuracy and characteristic fragmentation.






