The goal of the submitted project is namely:
a) Research of preparation of special cellulosic matrix (films, dimensional 3D-structures and dimensional textiles, composites and its combination with other biopolymers (natural polysaccharides and peptides), or other physiologically active substances.
b) Design of prototypes of matrixes applicable as matrixes for active dressings in wound healing, surgery, or matrixes for tissue engineering. The research will be focused on fading of optimal technology of preparation of matrixes, surface treatment of materials, and incorporation of additives, e.g. biologically active substances or nanoparticles. The matrixes can be applied further in combination with drugs with a purpose of prolongation and effectiveness of required therapy (systems of drug delivery).
c) Creation of conditions for further interdisciplinary cooperation in clinical research in wound healing, clinical microbiology, burn treatment and reconstructive surgery in Czech Republic and abroad.
d) Expansion of production program of a company Holzbecher spol. s r.o. barevna a bělidlo (division Medical) by prospective area of active wound healing and exploiting of built research capacities.

The main objective of the project is to develop simple and cheap physico-chemical methods for reactivating sorbent cartridge of adsorption columns used for capture of polar chlorinated compounds which increase the parameter AOX. Application of aqueous solutions of liquid ion exchangers and simple way for degradation of the concentrated AOX will be applied using the know-how of University of Pardubice and commercial organizations focusing on research in organic specialty chemicals production (Výzkumný ústav organických syntéz, a.s.). To reach the main objective will be developed (I) analytical methods for sample preparation, for characterization (compound identification) and quantification of AOX adsorbed on the activated carbon in the adsorption columns operated in an industrial scale in the production of organic chemical specialties (dyes and pigments), (II) technique of effective application of the liquid ion exchangers on the sorption packing, (III) regeneration technique for already used liquid ion exchangers followed by chemical decomposition of captured AOX (verified technology, patent application), (IV) development of a method of monitoring capacity of the sorbent cartridge for capture of specific AOX.

The project is focused on the removal of undesirable and/or biologically non-degradable contaminants occured in technological effluents and solid wastes. The typical representatives of these contaminants are polar and non-polar aromatic halogenoderivatives and similar compounds. The removal of contaminants is based on application of low-cost commercially available ionic liquids for sorption with appropriate subsequent reductive degradation of obtained products at room temperature and ambient pressure. The applied reagents are recyclable.

The aim of this project is to develop a new type of UV curable varnish for inkjet varnishing machines with the ability to print complex motifs of varnish effects (including 3D). The developed varnish will be cured with a combination of radical and cationic polymerization initiated by UV radiation. Currently, the majority of UV-curable inks and varnishes are cured by radical polymerization and only a small part by cation polymerization. The matter of curing UV-curable inkjet inks/varnishes is influenced by many parameters, which have to be taken into account during development (e.g. print head type, droplet size of ejected ink, viscosity, surface tension, mechanical properties of cured materials, etc.). A common practise is that the set parameters are mutually contradictory (e.g. flexibility of layers vs. surface resistance to scratching), therefore it is necessary to find a compromise. Today, a relatively large number of manufacturers of inkjet inks/varnishes can be found on the market (e.g. Sun Chemical, Toyo Ink, Chimigraf, Svang Ink, etc.). Nevertheless, due to differences between printing machines, printing heads, printed substrates and requirements on the final properties of cured inks and varnishes, it can be difficult to find an optimal varnish for a particular application. From performed market researches it is evident that there is a great demand for UV-curable varnish for pattern UV varnishing purposes. The developed hybrid UV varnish cured by radical and cationic polymerization simultaneously will be curable with medium-pressure mercury lamp (currently most frequently used UV source), and by diodes emitting in UV region (UV-LEDs) as well, which are considered to be highly perspective as a source for UV curing due to their advantages (long life, low energy consumption, instant on/off switching, no ozone generation etc.). This trend is indicated by increase of use of UV-LEDs in recent years and by gradual replacement of mercury lamps in some applications.

This project, based on primary research and marketing studies, suggests a comprehensive proposal for research and development of new systems for an efficient inhibition of wound pathogens biofilm, that is gentle for patients. The project will be based on the principle of biofilm inhibition by programmed release of iodine using time-dependent generation of iodine from iodide by an oxidative agents (e.g., iodate, photochemically produced by reactive forms of oxygen, organic peroxides) and by using the release control with the help of iodine-binding polymer matrix. Also the benefit of inhibition of bacterial quorum sensing communication on the system will be tested during the project. The project covers research and development of wound dressings for the purpose of production specific products in the field of medical devices with improved properties over existing products, including the development of verified technology of their production.

The aim of the project is functional sample three-axle chassis vof diesel locomotive 1520 mm for the markets of the former countries of the Soviet Union

The project is focused on the optimization of the synthesis of optically pure Corey alcohol-A (-), which is the basic raw material for the production of all human and veterinary prostaglandins as well.

The project deals the production of non-halogenated veterinary prostaglandins. These pharmaceutical active substances will be produced by patent easygoing synthesis with regard to green production process. The production of these substances help increase profitability of cattle, and secondarily reduce the burden on public health and the environment.

Technology of the continuous production of the printed memories elements and their implementation into flexible labels will be suggested. These labels enable high level of the product security and identification for the full automatized and robotized production and distribution process required by Industry 4.0 system. The security data will not be possible to change or forge and it will integrate the rewritable memory for the preservation of data enable to follow the product during its life cycle. Electronic security element will be supplemented by unique visual element. Reading device including software will be developed during the project for the reading and identification of the specific data stored in the memory system. Data will be read by contact way.