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Photoredox Catalyst based on pyrazin-2,3-dikarbonitril 

The novel organic catalyst can be used for photoredox reactions, preferably, the reactions selected from those utilising photoinduced electron transfer or energy transfer. It may facilitate or even allow common/novel laboratory/industrial synthetic processes and also replace organometallic species or xanthene dyes widely used in photoredox processes. It could be used in a range of applications including photovoltaics, therapeutics.              

In particular, the novel photoredox catylyst can be applied in the preparation of biologically and medicinally relevant tetrahydroisoquinoline (THIQ) derivatives. THIQ-based analogs exert antiproliferative and antimitotic effects, induce apoptosis and involve autophagic processes.

Purely organic, metal-free photoredox catalyst developed at Bures Group University of Pardubice now commercially available.