Dr. Patrik Pařík

phone: +420 46 603 7075
e-mail: Patrik.Parik@upce.cz
Born in Dvůr Králové nad Labem on November 12, 1970. Married, wife Jana, daughter Tereza (2002), gemini Ondřej and Marek (2006).
He graduated from University of Pardubice in 1994, Thesis entitled Effect of Medium and Substituents on Dissociation of Model N-phenylsulfonylbenzamides under supervision of Assoc. Prof. Dr. Miroslav Ludwig. In 1999 he defended his Ph.D. Thesis Study of Acid-Base Reactions of Substituted Naphthalenecarboxylic Acids (supervisor Assoc. Prof. Dr. Miroslav Ludwig).
He is interested in synthesis of model organic compounds (imidazolines and imidazoles), potentiometric titration in organic solvents, substituent and solvent effects, chemometrics. He is member of the Czech Chemical Society.
He leads courses Statistical evaluation of experimental data and Laboratory of physical methods in organic chemistry for undergraduate students in the specialization of Organic chemistry. He gives seminars from Organic chemistry I and II for bachelor students. He participates in teaching the courses Laboratory of organic chemistry I and II. In specialized courses for extramural bachelor students he gives lecturesOrganic chemistry I and Basics of organic synthesis.
He participates in organising of chemical seminars for secondary school teachers.
1. Ludwig M., Pařík P., Kulhánek J.: A Study of Transmission Effects of Sulfonyl and Carbonyl Groups. Collect. Czech. Chem. Commun. 1995, 60, 841.
2. Ludwig M., Pařík P.: Dissociation of Substituted N-phenylsulfonylbenzamides - Effects of Sulfonyl and Carbonyl Groups.Org. React. (Tartu) 1995, 29, 75.
3. Ludwig M., Pařík P.: Substituent Effects in the Naphthalene Series. Org. React. (Tartu) 1997, 31, 67.
4. Pařík P., Ludwig M.: Acid-base Properties of Substituted Naphthoic Acids in Nonaqueous Media. Collect. Czech. Chem. Commun. 1997, 62, 1737.
5. Ludwig M., Bednářová I., Pařík P.: Effect of Medium on Acid-catalyzed Decomposition of N-(Phenylazo)-substituted Nitrogen Heterocycles. Collect. Czech. Chem. Commun. 1999, 64, 1654.
6. Vlasák P., Pařík P., Klicnar J., Mindl J.: Synthesis of Ring-Substituted Phenyl Hydrazine-carboxylates and Study of Their Protonation in Dimethyl Sulfoxide Solutions. Collect. Czech. Chem. Commun.1998, 63, 793.
7. Pařík P., Wolfová J., Ludwig M.: Dissociation of Naphthoic Acids in Non-aqueous Media. Comparison of Benzene and Naphthalene Skeletons. Collect. Czech. Chem. Commun. 2000, 65, 385.
8. Pícha J., Cibulka R., Hampl F., Liška F., Pařík P., Pytela O.: Reactivity of p-Substituted Benzaldoximes in the Cleavage of p-Nitrophenyl Acetate: Kinetics and Mechanism. Collect. Czech. Chem. Commun.2004, 69, 397-413.
9. Perjéssy A., Fabian W. M. F., Pařík P., Ludwig M., Loos D., Šusteková Z.: Structure-Acidity-IR Spectra Correlations for p-Substituted N-Phenylsulfonylbenzamides. Molecules 2004, 9, 213-222.
10. Mansfeld M., Pařík P., Ludwig M.: Effect of para Substitution on Dissociation of N-Phenylbenzenesulfonamides. Collect. Czech. Chem. Commun.2004, 69, 1479-1490.
11. Pícha J., Cibulka R., Liška F., Pařík P., Pytela O.: Reparametrization and/or Determination of Hammett, Inductive, Mesomeric, and AISE Substituent Constants for Five Substituents: N+(CH3)3, CH2N+(CH3)3, CH2Py+, CH2SO2CH3 and PO(OCH3)2. Collect. Czech. Chem. Commun.2004, 69, 2239-2252.
12. Pařík P., Ludwig M.: Analysis of Substituent Effects in Naphthalene Skeleton. Collect. Czech. Chem. Commun. 2004, 69, 2297-2314.
13. Trögl J., Ripp S., Kuncová G., Sayler G. S., Churavá A., Pařík P., Demnerová K., Hálová J., Kubicová L.: Selectivity of whole cell optical biosensor with immobilized bioreporter Pseudomonas fluorescens HK44. Sens. Actuators B: Chem. 2005, 107, 98-103.
14. Böhm S., Pařík P., Exner O.: Range of validity of the Hammett equation: acidity of substituted ethynylbenzenes. New J. Chem. 2006, 30, 384-391.
15. Pařík P., Šenauerová S., Lišková V., Handlíř K., Ludwig M.: Study of Synthesis of 2-(2-Alkoxyphenyl)-1H-imidazoles. Comparison of Oxidative Aromatization Reactions of Imidazolines. J. Heterocyclic Chem. 2006, 43, 835-841.
16. Trögl J., Kuncová G., Kubicová L., Pařík P., Hálová J., Demnerová K., Ripp S., Sayler G. S.: Response of the Bioluminescent Bioreporter Pseudomonas Fluorescens HK44 to Analogs of Naphthalene and Salicylic Acid. Folia Microbiol. 2007, 52, 3-14.
17. Roušar T., Pařík P., Kučera O., Bartoš M., Červinková Z.: Glutathione reductase is inhibited by acetaminophen-glutathione conjugate in vitro. Physiological Research 2010, in press. (http://www.biomed.cas.cz/physiolres/accepted.htm)
Member of Academic Senate of Faculty of Chemical Technology (1998-2001, 2001-2004, 2007-2010)., member of Academic Senate board, FChT UPa (2002-2004, 2007-2010), chairman of Academic Senate board, FChT UPa (2009-2010).
Webmaster of institute web pages.